It’s shaping up to be one of the worst tick years yet, and concerns about Lyme disease—which is transmitted through the bites of some species—are high. Aside from a short-lived vaccine released in the late 1990s, people have not had the opportunity to get vaccinated against Lyme disease. But if our dogs can get vaccinated, why can’t we? Host Flora Lichtman speaks with immunologist and Lyme disease expert Linden Hu about the ongoing quest for a vaccine against Lyme disease, and our evolving understanding of the disease.  Guest: Dr. Linden Hu is a Professor of immunology at Tufts University School of Medicine.Read an article from SciFri about the research towards finding an anti-tick vaccine.Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

About 7% of veterans experience post-traumatic stress disorder (PTSD), and that number can be closer to 30% for those who have served in a war zone.  But PTSD has been treated pretty much the same way since the disorder was first recognized roughly four decades ago: Patients are instructed to revisit their trauma until the memory no longer creates an emotional response. This process can be so harrowing that over half of veterans are unable to complete the full course of treatment. But what if there was a way for PTSD treatment to be virtually painless?Host Flora Lichtman talks with Yasmin Tayag, staff writer at The Atlantic, who explored a controversial treatment called Reconsolidation of Traumatic Memories, and the challenges of even studying a treatment that bucks conventional wisdom.  Guest: Yasmin Tayag is a staff reporter for The Atlantic.Transcripts for each episode are available within 1-3 days at sciencefriday.com.  Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

For decades, astronomers have been trying to nail down the value of the Hubble constant—a measure of how fast the universe is expanding. But some cosmologists say there’s evidence that the universe is expanding faster than physics can explain, and our current models of it might be broken. Hosts Flora Lichtman and Ira Flatow talk with Wendy Freedman and Dan Scolnic, two cosmologists with different takes on this constant controversy.Guests: Wendy Freedman, a former team leader of the Hubble Key Project, is a professor of astronomy and astrophysics at the University of Chicago in Chicago, Illinois.Dr. Dan Scolnic is a cosmologist and associate professor of physics at Duke University in North Carolina.Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

Oceanographer Victoria Orphan’s dream was coming true. She was sitting in the Alvin submersible, on one of its deepest science dives ever. But the trip was anything but smooth sailing. Victoria takes us inside the sub, where her dream turns nightmarish as things start to go wrong, and Alvin pilot Nick O’Sadcia works frantically to troubleshoot. Oceanographer Shana Goffredi, who’s also Victoria’s wife, tells us about the tense scene unfolding on the ship miles above, as they wait for word from the sub. “The Leap” is a 10-episode audio series that profiles scientists willing to take big risks to push the boundaries of discovery. It has premiered on Science Friday’s podcast feed every Monday since May 12. This is the final episode of the 2025 season.“The Leap” is a production of the Hypothesis Fund, brought to you in partnership with Science Friday.Transcript is available on sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

Researchers found a new sea spider with a giant nose, leg cannons, and—most remarkably—a novel way of surviving in the lightless, freezing environment miles below the sea surface. These oceanic arthropods are powered by methane that seeps out of the ocean floor.Biologist Shana Goffredi joins Host Flora Lichtman to tell us more about the discovery and explain how we’re connected to these little beasts.Guest: Dr. Shana Goffredi is a biology professor at Occidental College in Los Angeles, CA.Transcripts for each episode are available within 1-3 days at sciencefriday.com.  Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

Most pasta is made from just two ingredients—flour and water. For decades this humble food has prompted physicists around the world to try to understand its mysterious properties and answer questions like: Why does a stick of spaghetti break into three pieces and not cleanly into two? And why is cacio e pepe so hard to perfect? The answers reveal more about the building blocks of the universe than you might expect. Host Ira Flatow talks with Joseph Howlett, math writer at Quanta Magazine, and author of a recent story for the BBC about spaghetti science.And, if you frequent the wellness world on social media, you may have seen a trend popular with influencers: using adhesive tape to seal one’s mouth shut while sleeping. This is intended to help the sleeper breathe through their nose all night, which people claim has a slew of benefits including improved quality of sleep, reduced sleep apnea, a more defined jawline, and a brightened complexion. But should you add mouth taping to your nighttime routine? According to Dr. Linda Lee, physician and surgeon at Massachusetts Eye and Ear in Boston, you should be evaluated by a professional first.Dr. Lee joins Host Flora Lichtman to talk about the right way to start nose breathing, what the scientific literature says (and doesn’t say) about mouth taping, and how social media is changing the information patients seek from their physicians. Transcripts for each episode are available at sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

We live in a world filled with microbes—they’re inside our bodies, in soil, in deep sea hydrothermal vents, and in your window AC unit. Some microbiologists are hopeful that finding more of these tiny organisms could help us address the climate crisis. Joining Host Flora Lichtman to talk about how are microbiologists James Henriksen and Lisa Stein.Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

GLP-1 medications like Ozempic have dominated headlines over the past couple of years. When writing his new book, Diet, Drugs and Dopamine: The New Science of Achieving a Healthy Weight, former FDA commissioner David Kessler wanted to unpack the science beyond those headlines. He also has a personal relationship with the subject, having taken GLP-1 medications himself. Host Flora Lichtman joins Kessler to talk about the latest science on metabolism, weight loss, and how these blockbuster drugs actually work.Guest: Dr. David Kessler is the former commissioner of the FDA and the author of Diet, Drugs and Dopamine: The New Science of Achieving a Healthy Weight.Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

In both her life and her work, researcher Karmella Haynes has never followed the pack. Karmella explains why she created her own area of research at the intersection of synthetic biology and epigenetics. Emory colleague David Katz weighs in on the challenges Karmella faces in pioneering a new research field. Plus Karmella’s sister Sherrone Wallace fills us in on their family life, and how their father raised them to inhabit spaces that weren’t always welcoming. Karmella has been recognized by the Hypothesis Fund as a Scout for her bold science and enabling others to pursue their big ideas. “The Leap” is a 10-episode audio series that profiles scientists willing to take big risks to push the boundaries of discovery. It premieres on Science Friday’s podcast feed every Monday until July 21. “The Leap” is a production of the Hypothesis Fund, brought to you in partnership with Science Friday.Transcript is available on sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

In excerpts of two conversations from the Science Friday archives (originally recorded in 2000 and 2009), oceanographer Robert Ballard joins Host Ira Flatow to discuss the 1985 expedition in which he discovered the wreck of the Titanic. He also emphasizes the value of combining the efforts of oceanographers, engineers, and social scientists to study the world’s deep oceans.Guest: Robert Ballard is a National Geographic Explorer-at-Large and a Professor of Oceanography in the Center for Ocean Exploration at the University of Rhode Island in Kingston, Rhode Island.Transcripts for each episode are available within 1-3 days at sciencefriday.com.  Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

Summer is here, which means it’s the season for soaking up the sun. But it’s important to do so responsibly, considering the strong link between sun exposure and skin cancer. There are a lot of sunscreens on the market, so Hosts Flora Lichtman and Ira Flatow join dermatologist Jonathan Ungar to discuss what ingredients to look for and how they work.Guest: Dr. Jonathan Ungar is a dermatologist and director of the Waldman Melanoma and Skin Cancer Center at Mount Sinai in New York, New York.Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

The latest Jurassic World movie, “Jurassic World Rebirth,” is out today. The movie stars Scarlett Johansson (“The Avengers”) and Mahershala Ali (“Moonlight”). Their characters make a dangerous journey to an island chock-full of dinosaurs to get their hands on some dino blood for a life-saving heart medicine. But unfortunately for them, and luckily for us, things do not go as planned.Producer Dee Peterschmidt saw the movie and has a behind-the-scenes look with the movie’s scientific consultant, paleontologist Steve Brusatte.Guest: Dr. Steve Brusatte is a paleontologist at the University of Edinburgh.Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.